Our reagents lyse viruses and cells without enzymes or harsh detergents, negating the need for traditional “capture & release” approaches.
THE SCIENCE OF NANOTECHNOLOGIES
The science of PCRopsis is performing simultaneous tasks without external sample manipulation.

Robust Sample Lysis

Disrupt Nucleic Acid Structure
Our reagents disrupt nucleic acid tertiary and quaternary structures to improve target accessibility.

Disassociate Protein
Our reagents remove nucleic acid bound proteins to improve target accessibility.

Stabilize Nucleic Acids
Our reagents minimize the effects of nucleases to minimize loss of target nucleic acids.

Sequester PCR Inhibitors
Our reagents bind to PCR inhibitors to prevent them from interfering with PCR applications.
White Papers and Studies
- PCRopsis™ Reagents Detect 3.9 viral copies / μL of SARS-CoV-2 in Transport Medium, Saliva, and Dried on Swabs
- PCRopsis™ Reagent RVD-RT Outperforms Promega XpressAmp™ for direct PCR applications at Room Temperature
- PCRopsis™ Reagent RVD-RT enables detection of less than 50 cfu / mL of gram positive and negative bacteria at room temperature
- PCRopsis™ Reagent RVD Facilitates RNA Extraction-free Amplification of Gene Targets from SARS-CoV-2
- PCRopsis™ Reagent RVD with RVD Enhancer Facilitates DNA Extraction-free Amplification of Bacterial Gene Targets
- PCRopsis™ Reagent RVD-RT Facilitates Visual Detection of SARSCoV-2 in Transport Medium using RT-LAMP
- PCRopsis™ Reagent RVD-E Enables Extraction-free Amplification of Gene Targets from Specimens on Swabs
- PCRopsis™ Reagent RVD with RVD Enhancer + PCRopsis™ Support enables direct amplification of bacteria from urine
- PCRopsis™ Reagent Buccal mediates direct PCR amplification of buccal sample, even when diluted 1 / 10 million
- PCRopsis™ Reagent RVD with RVD Enhancer facilitates extractionfree amplification of human and bacterial targets from blood dried on filter paper
- PCRopsis™ BCS Nano Produces Blood Cell Distributions Comparable to Buffy Coats without Centrifugation and Facilitates Next Gen Direct PCRT
- PCRopsis™ Support and Lysis Beads Offer Improved Detection of Difficult to Lyse Microorganisms
Next Gen Direct PCR™ - Reagents
PCRopsis ™ Reagent RVD with RVD Enhancer
Mediates extraction-free PCR / RT-qPCR from saliva, urine and swab samples in numerous transport mediums
PCRopsis ™ Reagent RVD-E
Mediates extraction-free PCR / RT-qPCR directly from dried swabs (no transport medium)
PCRopsis ™ Reagent Buccal
Mediates extraction-free PCR / RT-qPCR directly from dried buccal swabs (no transport medium)
PCRopsis ™ Reagent RVD-RT + PCRopsis ™ Activator
Mediates extraction-free PCR / RT-qPCR from saliva, urine and swab samples in numerous transport mediums (NO SAMPLE HEATING REQUIRED)
Sample Concentrating Technologies
PCRopsis ™ Concentrator
Concentrate DNA, protein and cellular samples without equipment
PCRopsis ™ BCS Nano
Enrich for WBC / nucleated cells from whole blood without equipment and compatible with automation
Supporting Technologies
PCRopsis ™ Elution Buffer
Sample elution buffer that’s proven compatible with PCRopsis™ technologies
PCRopsis ™ Support
Additive used in combination with PCRopsis™ technologies to improve select applications (e.g., direct PCR from urine samples)
PCRopsis ™ Activator
Additive used in combination with PCRopsis™ technology to mediate room temperature Next Gen Direct PCR
PCRopsis ™ Lysis Beads
Coated beads used to facilitate lysis of microorganisms
Sample Collection Technologies
PCRopsis ™ Oral Rinse
Collect and transport oral samples for testing (e.g., viral, bacterial, buccal, toxicology)
PCRopsis ™ Blood Kit
Extraction-Free PCR from Serum and Plasma
